Liposomes are microscopic vesicles that encapsulate and deliver bioactive agents.
Liposomes are very small, about the size of a grain of sand, and they are made from phospholipids. Lipids are the main constituents of vesicles and are similar to what makes up cell membranes. Liposomes are typically the size of a grain of sand.
The technology that Liposomes are based on is called ‘pharmaceutics’. This means that it is basically a way of encapsulating drugs inside the outer shell of the vesicle. You can think of liposomes as a combination of a drug and a delivery vehicle. As it’s a combination of drug and vehicle, it’s kind of the same idea as putting a bomb inside the vesicle’s outer shell.
It sounds like it would be an amazing drug delivery vehicle, but it’s not what it’s actually made of. When scientists made the first Liposomes, they were hoping to use them to deliver drugs by “inverting” the membrane. Their idea was that if they changed the vesicles’ composition so that it had a different ratio of components, then the drug could be delivered to its target.
The problem is that their idea was that the outer membranes of the vesicles were made of lipids and that the components inside were cholesterol so they couldn’t be altered. The lipid composition of the outside of the vesicles was what changed. This is why the drug cannot be delivered without breaking the vesicle’s membrane.
The liposomes themselves are not lipids. They are lipid vesicles. Also, I think this is the part of liposomal theory I want to rant about.
Liposomal drugs (which are just tiny, tiny vesicles) are considered to be safer because they are not completely biodegradable. They are still alive but they will not ever be completely biodegradable. There are many things that can be done to kill cancer cells including chemotherapy, radiation, and a host of other agents that are not considered to be safe. But these are not the real problems with liposomal drugs.
The real problem with liposomal drugs is that it is not completely safe. It is possible to make a liposome biodegrade rapidly and easily. It is also possible to make a liposome that does not kill cancer cells but is biodegradeable. There are lots of ways to make a liposome that is biodegradable, but the problem is that liposomes are not as stable as solid particles.
It turns out that Liposome Biodegradable Particle, or LBPP, is not really biodegradable. That means that they will just dissolve in your blood and that if you eat them they will simply get reabsorbed and eliminated from your body’s system.
The main problem with making a liposome biodegradable lies in the fact that it is hard to make a liposome that is biodegradable. By the time you have a liposome biodegradable, it is more likely that they will dissolve in your blood. That means that you need to take liposome and you need to make it biodegradable.